Desertification monitoring as a main portion for understand desertification, have been conducted by many scientists. However, the stage of research remains still in the level of comparison of the past and current situation. In other words, monitoring need to focus on finding methods of how to take precautions against desertification. In this study, Vegetation Temperature Condition Index (VTCI), derived from Normalized Difference Vegetation Index (NDVI) and Land Surface Temperature (LST), was utilized to observe the distribution change of vegetation. The index can be used to monitor drought occurrences at a regional level for a special period of a year, and it can also be used to study the spatial distribution of drought within the region. Techniques of remote sensing and Geographic Information System (GIS) were combined to detect the distribution change of vegetation with VTCI. As a result, assuming that the moisture condition is the only main factor that affects desertification, we found that the distribution of vegetation in Bulgan, Mongolia could be predicted in a certain degree, using VTCI. Although desertification is a complicated process and many factors could affect the result. This study is helpful to provide a strategic guidance for combating desertification and allocating the use of the labor force. Key Words : Desertification monitoring, Remote sensing, GIS, VTCI